AOP
BEPyBr
Boc酸酐
BOP
BOP-Cl
BrOP
CDI
CDP
CDT
CIB
CIP
Cl-HOBt
DCC
DCI
DEAD
DEPBT
DEPC
DFIH
DIC
DIEA
DMAP
DMT-Cl
DMTMM; DMT-MM
DSC
EDC.HCl
EEDQ
Fmoc-Cl
Fmoc-OSu
FMOH
HATU
HBTU
HBPipU
HBTPyU
HCTU
HOAt
HOBt
HONB
HOOBt
HOSU
HSPyU
HSTU
IIDQ
MEI
MMT
MSNT
NEPIS
PipClU
PTA
PyAOP
PyBOP
PyBrOP
PyClOP
QSC
Sulfo-NHS
TATU
TBTU
TBDMSCl
TCFH
TCTU
TDBTU
TFFH
Tfp-OH
TNTU
Tosylimidazole
TOTT
TOTU
TPSCl
TPSI
TPTU
Triphosgen
Trt-Cl
TSNT
TSTU

地址: 上海市中原路60弄1号中原大厦1106
邮编: 200438
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联系人: 郭学敏 先生
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产品名称: BOP

产品分类: 多肽试剂

产品目录: 40102


产品质量标准

产品名称

BOP;卡特缩合剂

化学名

Benzotriazole-1-yl-oxy-tris-(dimethylamino)-phosphonium hexafluorophosphate

CAS 序号 56602-33-6
分子式 C12H22F6N6OP2
分子量 442.5
外观 白色结晶性粉末
熔点 135~140 °C (dec.)
纯度 不低于99%
干燥失重 不高于0.5%
重金属 不高于20 ppm
包装 25g; 100g; 500g。1公斤/袋
贮存 阴凉干燥处保存
注意 过热易发生爆炸!干热超过100°C时应特别警惕!

小注:
Reagent for high yield, low racemisation peptide coupling[1], mild and efficient reagent for the preparation fo esters from carboxylic acids and alcohols[2]; for esterification of amino at low temperature[3], for use in formation of mixed phophonate diesters[4]. The carboxyphosphonium salts formed by reaction with carboxylic acids can be reduced with NaBH4, providing a mild method for reduction of acids to alcohols[5]. Promotes the reaction of aliphatic primary amines with CS2 to give isothiocyanates which can be isolated in high yield or reacted in situ with nucleophiles[6].

Ref:

  1. Tetrahedron Lett.  1219 (1975)
  2. Tetrahedron Lett.  36, 4253(1995)
  3. Tetrahedron Lett. 35, 5603(1994)
  4. J. Org. Chem., 60, 5214(1995)
  5. Tetrahedron Lett., 39, 3319(1988)
  6. J. Che. Soc., Chem. Commun., 1995(1995)
 
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