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共价化学公司产品应用实例(2014年度)
  1. An integrated giant magnetoimpedance biosensor for detection of biomarker.  Tao Wang, Zhen Yang, Chong Lei, Jian Lei, Yong Zhou.  Biosensors and Bioelectronics, 2014, 58, 338-344.  [NHS]
  2. A Monochromatic Electrochemiluminescence Sensing Strategy for Dopamine with Dual-Stabilizers-Capped CdSe Quantum Dots as Emitters.  Liu, S., Zhang, X., Yu, Y., & Zou, G..  Analytical chemistry, 2014, 86(5):2784-2788.  [EDC.HCl]
  3. Highly efficient covalent immobilization of catalase on titanate nanotubes.  Ai, Q., Yang, D., Li, Y., Shi, J., Wang, X., & Jiang, Z..  Biochemical Engineering Journal, 2014, 83, 8-15.  [EDC.HCl] [NHS]
  4. Biodegradable and thermosensitive polyaspartamide derivatives bearing aromatic structures.  Ma, Y., Jiang, X., & Zhuo, R..  Materials Letters, 2014, 121.  [CDI]
  5. Highly-selective electrochemical determination of catechol based on 3-aminophenylboronic acid-3,4,9,10-perylene tetracarboxylic acid functionalized carbon nanotubes modified electrode.  Wei Liu, Liang Wu, Xiaohua Zhang and Jinhua Chen.  Analytical Methods, 2014. 6(3):718-724.  [EDC.HCl]
  6. Horseradish peroxidase-loaded nanospheres attached to hollow gold nanoparticles as signal enhancers in an ultrasensitive immunoassay for alpha-fetoprotein.  Li, Y., Yuan, R., Chai, Y., Zhuo, Y., Su, H., & Zhang, Y..  Microchimica Acta, 2014, 181(5-6), 679-685.  [EDC.HCl] [NHS]
  7. Protection of photoactivity of photosensitizers by amphiphilic polysaccharide micelles.  Li, H. J., Yu, Z., Wang, S. P., & Zhang, L. M. .  Chinese Journal of Polymer Science, 2014, 32(10), 1413-1418. [EDC.HCl]
  8. Preparation, characterization, and highly effective mercury adsorption of L-cysteine-functionalized mesoporous silica.  Qing Li, Zheng Wang, Dong-Mei Fang, Hai-yun Qu, Yan Zhu, Hui-jun Zou, Yi-rui Chen, Yi-Ping Du and   Hui-lian Hu.  New Journal of Chemistry, 2014, 38, 248-254.  [DCC]  [DMAP]
  9. Sample Preincubation Strategy for Sensitive and Quantitative Detection of Clenbuterol in Swine Urine Using a Fluorescent Microsphere–Based Immunochromatographic Assay.  Deng, S. L., Shan, S., Xu, C. L., Liu, D. F., Xiong, Y. H., Wei, H., & Lai, W. H..  Journal of Food Protection®, 2014, 77(11), 1998-2003. [EDC.HCl]
  10. Synthesis and self-assembly of PAMAM/PAA Janus dendrimers.  Gao, C., Liu, M., Lü, S., Zhang, X., & Chen, Y..  Materials Research Express, 2014, 1(1): 015005.  [EDC.HCl] [NHS]
  11. Effect of physiochemical property of Fe 3 O 4 particle on magnetic lateral flow immunochromatographic assay. Yan, J., Liu, Y., Wang, Y., Xu, X., Lu, Y., Pan, Y., ... & Shi, D..  Sensors and Actuators B: Chemical, 2014, 197, 129-136. [EDC.HCl] [Sulfo-NHS]
  12. Fabrication CdS nanoparticles on the edges of reduced graphene oxide sheets with P2VP polymer brushes. Mater.  Yang, Y., Li, M., Xie, Y., Song, X., Qu, X., & Zhao, H. (2014).   [EDC.HCl] [NHS]
  13. In situ cross-linked polysaccharide hydrogel as extracellular matrix mimics for antibiotics delivery. Zhao, Y., Zhang, X., Wang, Y., Wu, Z., An, J., Lu, Z., ... & Li, C..  Carbohydrate polymers, 2014, 105, 63-69.[EDC.HCl] [HOBt]
  14. A reusable and portable immunosensor using personal glucose meter as transducer. Zhu, X., Zheng, H., Xu, H., Lin, R., Han, Y., Yang, G., ... & Chen, G..  Analytical Methods, 2014, 6(14), 5264-5268.  [EDC.HCl] [NHS]
  15.  Electrochemical determination of bleomycins based on dual-amplification of 4-mercaptophenyl boronic acid-capped gold nanoparticles and dopamine-capped gold nanoparticles. He, X., Liu, W., Zhang, X., Zhang, X., & Chen, J..  Anal. Methods, 2014, 6(17), 6893-6899.  [EDC.HCl]
  16. A pseudo triple-enzyme cascade amplified aptasensor for thrombin detection based on hemin/G-quadruplex as signal label. Yi, H., Xu, W., Yuan, Y., Bai, L., Wu, Y., Chai, Y., & Yuan, R..  Biosensors and Bioelectronics, 2014, 54, 415-420.  [EDC.HCl]
  17. A reagentless electrochemiluminescent immunosensor for apurinic/apyrimidinic endonuclease 1 detection based on the new Ru (bpy) 3 2+/bi-arginine system. Zhao, M., Chai, X. D. Y. Q., Han, J., Gui, G. F., Yuan, R., & Zhuo, Y..  Analytica chimica acta, 2014, 846, 36-43.  [EDC.HCl] [NHS]
  18. A super intramolecular self-enhanced electrochemiluminescence immunosensor based on polymer chains grafted on palladium nanocages. Wang, H., He, Y., Chai, Y., & Yuan, R..  Nanoscale, 2014, 6(17), 10316-10322.  [EDC.HCl] [NHS]
  19. Chitosan-Modified Cationic Amino Acid Nanoparticles as a Novel Oral Delivery System for Insulin. Abbad, S., Zhang, Z., Waddad, A. Y., Munyendo, W. L., Lv, H., & Zhou, J.   Journal of Biomedical Nanotechnology, 2014, 11(3), 486-499. [EDC.HCl]
  20. Amplified impedimetric DNA sensor based on graphene oxide–phenylboronic acid for sensitive detection of bleomycins. Liu, W., Zhang, Y., Zhang, X., He, X., Zhang, X., & Chen, J.  New Journal of Chemistry, 2014, 38(6), 2284-2291.[EDC.HCl]
  21. Biological assessment in-vivo of gel-HA scaffold materials containing nano-bioactive glass for tissue engineering. Zhou, Z., Xiang, L., Ou, B., Huang, T., Zhou, H., Zeng, W., ... & Huang, H., Journal of Macromolecular Science, Part A, 2014, 51(7), 572-576.  [EDC.HCl]
  22. Carbon Quantum Dot Stabilized Gadolinium Nanoprobe Prepared via a One-Pot Hydrothermal Approach for Magnetic Resonance and Fluorescence Dual-Modality Bioimaging. Xu, Y., Jia, X. H., Yin, X. B., He, X. W., & Zhang, Y. K., Analytical chemistry, 2014, 86(24), 12122-12129.   [DCC]
  23. Non-covalent modification of thrombolytic agent nattokinase: simultaneous improvement of fibrinolysis activity and enzymatic stability. Chen, C., Duan, H., Gao, C., Liu, M., Wu, X. A., Wei, Y., ... & Liu, Z., RSC Advances, 2014, 4(52), 27422-27429.  [NHS]
  24. Chitosan Surface-Modified PLGA Nanoparticles: Preparation, Characterization, and Evaluation of their In Vitro Drug-Release Behaviors and Cytotoxicities. Chen, H. L., Wang, Y. X., Zhou, P., Liu, R., Nan, W. B., Wang, Y. S., ... & Zhang, Q. Q., Current Nanoscience, 2014, 10(2), 255-262.  [EDC.HCl] [NHS]
  25. Preparation and characterization of ultrasensitive and specific polyclonal antiserum against ciprofloxacin based on cationized bovine serum albumin. Deng, S. L., Li, P., Liu, H. B., & Yang, S. M. , Chemical Papers, 2014, 68(11), 1505-1513.[EDC.HCl] [Sulfo-NHS]
  26. Development of multifunctional folate-poly (ethylene glycol)-chitosan-coated Fe3O4 nanoparticles for biomedical applications. Zhou, S., Li, Y., Cui, F., Jia, M., Yang, X., Wang, Y., ... & Hou, Z., Macromolecular Research, 2014, 22(1), 58-66.  [EDC.HCl] [NHS] [DCC]
  27. Influence of Layer-by-Layer Polyelectrolyte Deposition and EDC/NHS Activated Heparin Immobilization onto Silk Fibroin Fabric. Elahi, M. F., Guan, G., Wang, L., & King, M. W. , Materials, 2014, 7(4), 2956-2977.  [EDC.HCl] [NHS]
  28. Evaluation of antibacterial activity of N-phosphonium chitosan as a novel polymeric antibacterial agent. Guo, A., Wang, F., Lin, W., Xu, X., Tang, T., Shen, Y., & Guo, S., International journal of biological macromolecules, 2014, 67, 163-171.  [EDC.HCl] [HOBt]
  29. Galactosylated reduction and pH dual-responsive triblock terpolymer Gal-PEEP-a-PCL-ss-PDMAEMA: a multifunctional carrier for the targeted and simultaneous delivery of doxorubicin and DNA. Zhang, Y., He, J., Cao, D., Zhang, M., & Ni, P., Polymer Chemistry, 2014, 5(17), 5124-5138.  [CDI]
  30. Glucose-sensitive polyelectrolyte nanocapsules based on layer-by-layer technique for protein drug delivery. Guo, H., Guo, Q., Chu, T., Zhang, X., Wu, Z., & Yu, D., Journal of Materials Science: Materials in Medicine, 2014, 25(1), 121-129. [EDC.HCl] [NHS]
  31. Hollow platinum decorated Fe 3 O 4 nanoparticles as peroxidase mimetic couple with glucose oxidase for pseudobienzyme electrochemical immunosensor. Yang, Z., Chai, Y., Yuan, R., Zhuo, Y., Li, Y., Han, J., & Liao, N., Sensors and Actuators B: Chemical, 2014, 193, 461-466.  [EDC.HCl] [NHS]
  32. Hydroxyethyl starch conjugates for improving the stability, pharmacokinetic behavior and antitumor activity of 10-hydroxy camptothecin. Li, G., Li, Y., Tang, Y., Zhang, Y., Zhang, Y., Yin, T., ... & Tang, X., International journal of pharmaceutics, 2014, 471(1), 234-244.  [EDC.HCl] [NHS] [DMAP]
  33. In vivo MRI detection of carotid atherosclerotic lesions and kidney inflammation in ApoE-deficient mice by using LOX-1 targeted iron nanoparticles. Wen, S., Liu, D. F., Cui, Y., Harris, S. S., Chen, Y. C., Li, K. C., ... & Teng, G. J., Nanomedicine: Nanotechnology, Biology and Medicine, 2014, 10(3), 639-649.  [EDC.HCl] [Sulfo-NHS]
  34. Influence of Nano-Bioactive Glass (NBG) Content on Properties of Gelatin-Hyaluronic Acid/NBG Composite Scaffolds. Zhou, Z., He, S., Ou, B., Huang, T., Zeng, W., Liu, L., ... & Cao, D., Journal of Macromolecular Science, Part B, 2014, 53(6), 1145-1155.  [EDC.HCl]
  35. Investigation of targeted biomolecules in a micro-fluxgate-based bio-sensing system. Lei, J., Lei, C., Wang, T., Yang, Z., & Zhou, Y. , Biomedical microdevices, 2014, 16(2), 237-243.  [Sulfo-NHS]
  36. A novel melphalan polymeric prodrug: Preparation and property study. Li, D., Lu, B., Huang, Z., Xu, P., Zheng, H., Yin, Y., ... & Xiong, F., Carbohydrate polymers, 2014, 111, 928-935.  [Fmoc-Osu] [DIC] [HBTU] [DMAP] [DIEA]
  37. Hydroxyethyl starch-10-hydroxy camptothecin conjugate: synthesis, pharmacokinetics, cytotoxicity and pharmacodynamics research. Li, G., Cai, C., Qi, Y., & Tang, X. , Drug delivery, 2014, (0), 1-8.  [EDC.HCl] [NHS] [DMAP]
  38. Determination of Hg 2+ by on-line separation and pre-concentration with atmospheric-pressure solution-cathode glow discharge atomic emission spectrometry. Li, Q., Zhang, Z., & Wang, Z. , Analytica chimica acta, 2014, 845, 7-14.  [DCC]  [DMAP]
  39. A Complementary Strategy for Enhancement of Nanoparticle Intracellular Uptake. Li, Y., Wen, G., Wang, D., Zhang, X., Lu, Y., Wang, J., ... & Wang, Y. , Pharmaceutical research, 2014, 31(8), 2054-2064.  [EDC.HCl] [NHS] [DMAP]
  40. Preparation of water-soluble β-cyclodextrin/poly (acrylic acid)/graphene oxide nanocomposites as new adsorbents to remove cationic dyes from aqueous solutions. Liu, J., Liu, G., & Liu, W. , Chemical Engineering Journal, 2014, 257, 299-308.  [EDC.HCl]
  41. Synthesis and characterization of lysine-modified SBA-15 and its selective adsorption of scandium from a solution of rare earth elements. Ma, J., Wang, Z., Shi, Y., & Li, Q. , RSC Advances, 2014, 4(78), 41597-41604.  [DCC]  [DMAP]
  42. Merging of covalent cross-linking and biomimetic mineralization into an LBL self-assembly process for the construction of robust organic–inorganic hybrid microcapsules. Tian, C., Zhang, C., Wu, H., Song, Y., Shi, J., Wang, X., ... & Jiang, Z.,  Journal of Materials Chemistry B, 2014, 2(27), 4346-4355. [EDC.HCl] [NHS]
  43. Modification of Polycaprolactone Microspheres-Aggregated Scaffolds with Galactosylated Chitosan for Modulating the Differentiation of Bone Mesenchymal Stem Cells. Wang, M., Ma, L., Li, B., & Gao, C., Journal of Biomaterials and Tissue Engineering, 2014, 4(8), 657-662.  [EDC.HCl] [NHS]
  44. Novel Ferrocenyl-Terminated Linear–Dendritic Amphiphilic Block Copolymers: Synthesis, Redox-Controlled Reversible Self-Assembly, and Oxidation-Controlled Release. Chang, X., Dong, R., Ren, B., Cheng, Z., Peng, J., & Tong, Z., Langmuir, 2014, 30(29), 8707-8716.  [DMAP]
  45. On-line separation and preconcentration of hexavalent chromium on a novel mesoporous silica adsorbent with determination by solution-cathode glow discharge-atomic emission spectrometry.  Ma, J., Wang, Z., Li, Q., Gai, R., & Li, X., Journal of Analytical Atomic Spectrometry, 2014, 29, 2315-2322.  [DCC]  [DMAP]
  46. Quenching of the emission of peroxydisulfate system by ferrocene functionalized chitosan nanoparticles: A sensitive “signal off” electrochemiluminescence immunosensor. Zhuo, Y., Han, J., Tang, L., Liao, N., Gui, G. F., Chai, Y. Q., & Yuan, R., Sensors and Actuators B: Chemical, 2014, 192, 791-795. [EDC.HCl] [NHS]
  47. Sandwich-format electrochemiluminescence assays for tumor marker based on PAMAM dendrimer-l-cysteine-hollow gold nanosphere nanocomposites. Zhuo, Y., Gui, G., Chai, Y., Liao, N., Xiao, K., & Yuan, R., Biosensors and Bioelectronics, 2014, 53, 459-464.  [EDC.HCl] [NHS]
  48. Detection of melamine by a magnetic relaxation switch assay with functionalized Fe/Fe 3 O 4 nanoparticles. Shen, J., Zhang, Y., Yang, H., Yang, Y., Zhou, Z., & Yang, S., Sensors and Actuators B: Chemical, 2014, 203, 477-482.  [EDC.HCl] [NHS]
  49. Signal-on electrochemical immunoassay for APE1 using ionic liquid doped Au nanoparticle/graphene as a nanocarrier and alkaline phosphatase as enhancer. Zhong, Z., Li, M., Qing, Y., Dai, N., Guan, W., Liang, W., & Wang, D., Analyst, 2014, 139(24), 6563-6568.  [EDC.HCl] [NHS]
  50. Star‐Shape Redox‐Responsive PEG‐Sheddable Copolymer of Disulfide‐Linked Polyethylene Glycol‐Lysine‐di‐Tocopherol Succinate for Tumor‐Triggering Intracellular Doxorubicin Rapid Release: Head‐to‐Head Comparison. Ai, X., Sun, J., Zhong, L., Wu, C., Niu, H., Xu, T., ... & He, Z., Macromolecular bioscience, 2014, 14(10), 1415-1428. [EDC.HCl]  [DMAP]
  51. Synthesis and Controlled Release of 5-Fluorouracil from Hydroxyethylchitosan: Based Polymer Prodrug[C]//Proceedings of the 2012 International Conference on Applied Biotechnology (ICAB 2012). Peng, Y., Liu, W., Han, B., & Zhou, R., Springer Berlin Heidelberg, 2014: 749-756. [NMP]
  52. Galactosylated biodegradable poly (ε-caprolactone-co-phosphoester) random copolymer nanoparticles for potent hepatoma-targeting delivery of doxorubicin. Tao, Y., He, J., Zhang, M., Hao, Y., Liu, J., & Ni, P. , Polymer Chemistry, 2014, 5(10), 3443-3452.  [EDC.HCl]
  53. The Bifunctional Liposomes Constructed by Poly (2-ethyl-oxazoline)-cholesteryl Methyl Carbonate: an Effectual Approach to Enhance Liposomal Circulation Time, pH-Sensitivity and Endosomal Escape. Xu, H., Zhang, W., Li, Y., Fei, F. Y., Yin, P. P., Yu, X., ... & Shang, D. J., Pharmaceutical research, 2014, 31(11), 3038-3050.  [DMAP]
  54. Turn-On Detection of a Cancer Marker Based on Near-Infrared Luminescence Energy Transfer from NaYF4: Yb, Tm/NaGdF4 Core–Shell Upconverting Nanoparticles to Gold Nanorods. Chen, H., Guan, Y., Wang, S., Ji, Y., Gong, M., & Wang, L., Langmuir, 2014, 30(43), 13085-13091.  [EDC.HCl]
  55. Uptake, transport and peroral absorption of fatty glyceride grafted chitosan copolymer–enoxaparin nanocomplexes: Influence of glyceride chain length. Wang, L., Sun, Y., Shi, C., Li, L., Guan, J., Zhang, X., ... & Mao, S., Acta biomaterialia, 2014, 10(8), 3675-3685.  [EDC.HCl] [NHS]
  56. Trypsin-inspired poly (urea-urethane) s containing phenylalanine-lysine ethyl ester-phenylalanine units. Wang, F., Zheng, Z., Wang, W., Gu, Z., Wang, J., & Wang, X. , Polymer Degradation and Stability, 2014, 100, 86-92.  [EDC.HCl] [NHS]
  57. Tumor penetrability and anti-angiogenesis using iRGD-mediated delivery of doxorubicin-polymer conjugates. Wang, K., Zhang, X., Liu, Y., Liu, C., Jiang, B., & Jiang, Y. , Biomaterials, 2014, 35(30), 8735-8747.  [EDC.HCl]
  58. Development of biodegradable polymeric implants of RGD-modified PEG-PAMAM-DOX conjugates for long-term intratumoral release. Wang, K., Zhang, X., Zhang, L., Qian, L., Liu, C., Zheng, J., & Jiang, Y. , Drug delivery, 2014, (0), 1-11.  [EDC.HCl]
  59. In vitro and in vivo evaluation of chitosan graft glyceryl monooleate as peroral delivery carrier of enoxaparin. Wang, L., Li, L., Sun, Y., Ding, J., Li, J., Duan, X., ... & Mao, S. , International journal of pharmaceutics, 2014, 471(1), 391-399.  [EDC.HCl] [NHS]
  60. Gene-modified cell detachment on photoresponsive hydrogels strengthened through hydrogen bonding. Wang, N., Zhang, J., Sun, L., Wang, P., & Liu, W. , Acta biomaterialia, 2014, 10(6), 2529-2538.  [DMAP]
  61. Surface glycosylation of poly (3-hydroxybutyrate-co-4-hydroxybutyrate) membrane for selective adsorption of low-density lipoprotein. Wang, W., & Lan, P. , Journal of Biomaterials Science, Polymer Edition, 2014, 25(18), 2094-2112.  [EDC.HCl] [NHS]
  62. Bioinspired Approach to Multienzyme Cascade System Construction for Efficient Carbon Dioxide Reduction. Wang, X., Li, Z., Shi, J., Wu, H., Jiang, Z., Zhang, W., ... & Ai, Q. , ACS Catalysis, 2014, 4(3), 962-972.  [EDC.HCl] [NHS]
  63. Stable and Sensitive Silver Surface Plasmon Resonance Imaging Sensor Using Trilayered Metallic Structures. Wang, Z., Cheng, Z., Singh, V., Zheng, Z., Wang, Y., Li, S., ... & Zhu, J. , Analytical chemistry, 2014, 86(3), 1430-1436.  [EDC.HCl] [Sulfo-NHS]
  64. Electrochemiluminescence immunosensor using poly (l-histidine)-protected glucose dehydrogenase on Pt/Au bimetallic nanoparticles to generate an in situ co-reactant. Xiao, L., Chai, Y., Wang, H., & Yuan, R. , Analyst, 2014, 139(16), 4044-4050.  [EDC.HCl] [NHS]
  65. Fabrication and Properties of Porous Collagen/Hyaluronic Composite Scaffolds Containing Nano-Bioactive Glass for Tissue Engineering. Xiong, L., & He, Z. , Journal of Macromolecular Science, Part A, 2014, 51(11), 891-897.  [EDC.HCl]
  66. Amphiphilic polyethylenimine (PEI) as highly efficient non-viral gene carrier. Yan, X., Zhang, Y., Zhang, H., Wang, P. G., Chu, X., & Wang, X. , Organic & biomolecular chemistry, 2014, 12(12), 1975-1982.  [DCC]  [DMAP] [CDI]
  67. Enhanced thermal stability of organogels through self-reinforcing supramolecular assembly of a cholesterol–polyoxomatalate–cholesterol hybrid gelator. Yang, H. K., Su, M. M., Ren, L. J., Zheng, P., & Wang, W. , RSC Advances, 2014, 4(3), 1138-1145.  [EEDQ]
  68. Signal on fluorescence biosensor for MMP-2 based on FRET between semiconducting polymer dots and a metal organic framework. Yang, W., Zhang, G., Weng, W., Qiu, B., Guo, L., Lin, Z., & Chen, G. , RSC Advances, 2014, 4(102), 58852-58857.  [EDC.HCl] [NHS]
  69. High throughput immunosenor based on multi-label strategy and a novel array electrode. Yang, Z. H., Zhuo, Y., Chai, Y. Q., & Yuan, R. , Scientific reports, 2014, 4, Article number: 4747  [EDC.HCl] [NHS]
  70. Amplified amperometric aptasensor for selective detection of protein using catalase-functional DNA–PtNPs dendrimer as a synergetic signal amplification label. Zhang, J., Yuan, Y., Chai, Y., & Yuan, R. , Biosensors and Bioelectronics, 2014, 60, 224-230.  [EDC.HCl] [NHS]
  71. Preparation and application of sunset yellow imprinted ionic liquid polymer− ionic liquid functionalized graphene composite film coated glassy carbon electrodes. Zhao, L., Zhao, F., & Zeng, B. , Electrochimica Acta, 2014, 115, 247-254.  [EDC.HCl]
  72. Iron/iron oxide core/shell nanoparticles for magnetic targeting MRI and near-infrared photothermal therapy. Zhou, Z., Sun, Y., Shen, J., Wei, J., Yu, C., Kong, B., ... & Wang, W., Biomaterials, 2014, 35(26), 7470-7478.  [EDC.HCl] [NHS]
  73. Signal Amplification Strategy with Synergistic Catalysis of Hollow Pt Nanochains and Hemoglobin for Electrochemical Immunosensor. Zhuo, Y., Han, J., Yu, Y. Q., Chai, Y. Q., & Yuan, R. , Journal of The Electrochemical Society, 2014, 161(1), B26-B30.[EDC.HCl] [NHS]
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